. 2013 Jun 13;178(3):359–371. doi: 10.1093/aje/kws471

Table 1.

Clinical Characteristics of 7,698 Invasive Breast Cancer Cases Diagnosed Between 1995 and 2006 in the NIH-AARP Diet and Health Study Cohort^a

	Histological Type
	Ductal		Mucinous		Tubular		Lobular		Mixed Ductal-Lobular		Other
	No.	%^b	No.	%^b	No.	%^b	No.	%^b	No.	%^b	No.	%^b
Distribution of cases	5,334	69^c	216	3^c	132	2^c	836	11^c	639	8^c	541	7^c
Tumor stage at initial diagnosis or treatment
Local	2,649	73	132	92	86	95	363	62	256	63	212	63
Regional	886	24	8	6	5	5	194	33	140	34	86	25
Distant	88	2	3	2	0	0	26	4	11	3	41	12
Missing data	1,711		73		41		253		232		202
Tumor grade
1	1,142	23	85	63	87	87	124	26	123	22	59	17
2	2,209	44	39	29	12	12	248	53	308	55	110	32
3	1,527	31	8	6	1	1	88	19	117	21	163	47
4	87	2	2	1	0	0	12	3	9	2	17	5
Missing data	369		82		32		364		82		192
ER status^d
ER+	2,218	81	101	93	63	94	424	96	354	93	134	64
ER−	519	19	8	7	4	6	19	4	26	7	75	36
Borderline	4	0	0	0	0	0	0	0	0	0	1	0
Missing data	672		29		20		101		67		118
PR Status^d
PR+	1,835	69	84	81	51	77	326	76	277	78	107	52
PR−	827	31	20	19	15	23	102	24	78	22	98	47
Borderline	12	0	0	0	0	0	3	1	2	1	2	1
Missing data	739		34		21		113		90		121
ER and PR status^d
ER+/PR+	1,779	67	83	81	50	76	321	75	273	76	100	48
ER+/PR−	357	13	12	12	12	18	85	20	57	16	31	15
ER−/PR+	47	2	0	0	1	2	2	0	4	1	7	3
ER−/PR−	469	18	8	8	3	5	17	4	21	6	66	32
ER or PR borderline	16	1	0	0	0	0	3	1	2	1	3	1
Missing data	745		35		21		116		90		121

Abbreviations: ER, estrogen receptor; IQR, interquartile range; NIH, National Institutes of Health; PR, progesterone receptor.

^a The median ages at diagnosis for women with ductal, mucinous, tubular, lobular, mixed ductal-lobular, and other types of tumors were 68 (IQR, 64–72), 69 (IQR, 66–73), 69 (IQR, 63–72), 69 (IQR, 64–72), 68 (IQR, 64–72), and 68 (IQR, 64–72) years, respectively.

^b Percentages may not add up to 100 because of rounding.

^c Row percentage.

^d Calculated only among cases reported by registries that collected hormone receptor information (California; Louisiana; New Jersey; North Carolina; Nevada; Arizona; Atlanta, Georgia; and Detroit, Michigan).