Table 1.
Demographic and Clinical Characteristics of bAVM Cases for Combined Cohort Stratified by HHT Status
| Characteristics | Total (n = 1989) | HHT (n= 56) | Non-HHT (n = 1933) | P Value |
|---|---|---|---|---|
| Demographic | ||||
| Gender | ||||
| Male (#, %) | 1021 (51) | 23 (41) | 998 (52) | 0.119 |
| Female (#, %) | 968 (49) | 33 (59) | 935 (48) | |
| Age at presentation (decades, SD) | 3.65 ± 1.8 | 2.87 ± 1.6 | 3.67 ± 1.8 | 0.002 |
| Ethnicity | 0.334 | |||
| Caucasian (#, %) | 374 (19) | 7 (13) | 367 (19) | |
| Black (#, %) | 51 (3) | 0 (0) | 51 (3) | |
| Hispanic (#, %) | 184 (9) | 2 (4) | 182 (9) | |
| Asian (#, %) | 97 (5) | 1 (2) | 96 (5) | |
| American Indian (#, %) | 9 (0.5) | 0 (0) | 9 (1) | |
| Unknown* (#, %) | 1267 (64) | 41 (81) | 1226 (63) | |
| Clinical | ||||
| HHT diagnosis | ||||
| No (#, %) | 1933 (97) | |||
| Yes (#, %) | 56 (2.8) | |||
| Multiple bAVMs | < 0.001 | |||
| No (#, %) | 1952 (98) | 34 (61) | 1918 (99) | |
| Yes (#, %) | 37 (1.9) | 22 (39) | 15 (1) | |
| Number of bAVMs | < 0.001 | |||
| 1 (#, %) | 1952 (98) | 34 (61) | 1918 (99) | |
| 2 (#, %) | 25 (1) | 14 (25) | 11 (< 1) | |
| 3 (#, %) | 7 (<1) | 5 (8) | 2 (< 1) | |
| 4 (#, %) | 4 (<1) | 2 (4) | 2 (< 1) | |
| ≥ 4 (#, %) | 1 (<1) | 1 (2) | 0 (0) | |
| Angiography | 0.395 | |||
| No (#, %) | 439 (22) | 9 (17) | 430 (22) | |
| Yes (#, %) | 1544 (78) | 43 (83) | 1501 (78) | |
| Symptomatic Presentation | 0.032 | |||
| No (#, %) | 436 (22) | 18 (34) | 418 (22) | |
| Yes (#, %) | 1549 (78) | 35 (66) | 1514 (78) | |
| Hemorrhagic Presentation | 0.065 | |||
| No (#, %) | 1183 (60) | 40 (71) | 1143 (59) | |
| Yes (#, %) | 806 (40) | 16 (29) | 790 (41) | |
*
No available information existed about the ethnicities of patients from the UHN cohort