Table 4.

Results of using bAVM Multiplicity for the Diagnosis of HHT.

Diagnostic	Univariate Model	95% CI	Multivariable Model*	95% CI
Sensitivity	0.393	0.265–0.532	0.340	0.212–0.488
Specificity	0.992	0.987–0.996	0.998	0.995–0.999
PPV	0.595	0.421–0.752	0.810	0.581–0.946
NPV	0.983	0.976–0.988	0.983	0.976–0.988
Positive LR	50.63	20.25–81.01	160.40	−8.40–329.19
Negative LR	0.61	0.48–0.74	0.66	0.53–0.79

^*Includes age in decades, symptomatic presentation, bAVM multiplicity, and cohort site