Table 1.
Gene | Location of proteina | Identified protein domainsb | Predicted functionb | Similar genes in other bacteriab |
---|---|---|---|---|
Hms locus: | ||||
hmsH | OM | - | ECM synthesis | pgaA (E. coli) |
hmsF | OM | polysaccharide deacetylase, COG1649 | ECM synthesis | pgaB (E. coli) icaB (Staph) |
hmsR | IM | glycosyl transferase | ECM synthesis | pgaC (E. coli) icaA (Staph) |
hmsS | IM | - | ECM synthesis | pgaD (E. coli) |
Unlinked gene: | ||||
hmsT | IM | GGDEF | Diguanylate cyclase | |
hmsP | IM | GGDEF, EAL | Cyclic-di-GMP phosphodiesterase | yhjK (E. coli) |
OM, outer membrane; IM, inner membrane
See text for references