Figure 1.

Characterization of Good Manufacturing Practice-derived fibroblasts reprogrammed to hiPSC cells using pluripotency markers confirms their undifferentiated status. (A): Phase contrast images of fibroblasts and the lower panel show their respective immune-stained hiPSC lines. #1001 and #1002 represent the human skin biopsy-derived fibroblasts. Fibrogro is xenofree fibroblasts, and XiPSC2 and XiPSC3 are the xeno-free hiPSC clones derived from normal human dermal fibroblasts under Good Manufacturing Practices conditions. (B): Immunostaining for markers typical of human pluripotent stem cells indicated reprogramming of the target fibroblasts.