TABLE 1.
BASELINE PHYSIOLOGIC CHARACTERISTICS
| |
Tracheal |
Nasal |
||||||
|---|---|---|---|---|---|---|---|---|
| Control | Pam2/ODN | Virus | Pam2/ODN + Virus | Control | Pam2/ODN | Virus | Pam2/ODN + Virus | |
| Ppeak |
90.0 (2.9) |
99.0 (1.0) |
159.6 (13.8)* |
133.5 (11.7) |
82.5 (4.4) |
80.0 (7.3) |
115.0 (19.1) |
101.7 (6.0) |
| HR |
278.8 (1.3) |
298.8 (5.2) |
297.7 (8.3) |
306.7 (4.3) |
273.3 (14.4) |
291.7 (11.8) |
288.3 (11.7) |
300.8 (12.9) |
| SBP |
47.8 (1.4) |
47.5 (2.9) |
51.4 (3.0) |
52.3 (3.1) |
42.0 (2.9) |
49.9 (2.8) |
46.3 (2.0) |
51.3 (3.6) |
| DBP |
24.0 (2.0) |
22.5 (1.0) |
25.2 (2.4) |
27.0 (2.1) |
19.8 (1.5) |
26.3 (2.8) |
29.0 (2.3) |
27.3 (3.0) |
| Weight | 0.371 (0.0004) | 0.381 (0.013) | 0.345 (0.007) | 0.3734 (0.018) | 0.371 (0.022) | 0.377 (0.026) | 0.356 (0.019) | 0.354 (0.007) |
Definition of abbreviations: DBP, diastolic blood pressure; HR, heart rate; ODN, ODN2395; Pam2, Pam2CSK4; Ppeak, Peak pulmonary pressure; SBP, systolic blood pressure.
Baseline data represent the means ± SEMs before pharmacologic manipulation.
*
P < 0.05, compared with control samples.