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SPLUNC1 is reduced in pneumonia. Pneumonia was induced in C57BL/6 mice with Pseudomonas aeruginosa (4 hours, n = 10 mice/group), Streptococcus pneumoniae (3 days, n = 4–5 mice/group), and influenza A virus (7 days, n = 4 mice/group). Control mice received PBS (S. pneumoniae and influenza A) or no treatment (P. aeruginosa). SPLUNC1 was measured in bronchoalveolar lavage fluid (BALF) by ELISA. Mean values are representative of 2–3 experiments. *P < 0.05.
