Table 2.

IVUS findings

	Sirolimus (N=61)	CNI (N=85)	P
IVUS follow-up period, yrs	2.9 (2.0, 3.6)	2.3 (1.7, 3.2)	0.11
Vessel volume index
Baseline, mm3/mm	16.7±4.7	16.8±4.8	0.91
Follow-up, mm3/mm	16.7±5.1	17.2±4.3	0.58
Change from baseline, mm3/mm	0.0±3.6	0.3±3.0	0.10
Lumen volume index
Baseline, mm3/mm	12.2±4.1	12.1±4.2	0.91
Follow-up, mm3/mm	11.2±4.1	11.2±3.6	0.95
Change from baseline, mm3/mm	−0.9±3.6*	−0.9±3.2*	0.98
Plaque volume index
Baseline, mm3/mm	4.6±2.4	4.8±2.5	0.76
Follow-up, mm3/mm	5.4±2.8	6.0±3.0	0.25
Change from baseline, mm3/mm	0.8±1.5‡	1.2±1.6‡	0.004
Plaque components
Fibrous
Baseline, mm3/mm	0.5 (0.0, 1.4)	0.6 (0.0, 1.8)	0.37
Follow-up, mm3/mm	0.9 (0.2, 2.2)	1.1 (0.2, 2.4)	0.50
Change from baseline, mm3/mm	0.4±1.0†	0.4±1.2‡	0.42
Fibrofatty
Baseline, mm3/mm	0.1 (0.0, 0.2)	0.1 (0.0, 0.3)	0.30
Follow-up, mm3/mm	0.1 (0.0, 0.2)	0.1 (0.0, 0.3)	0.16
Change from baseline, mm3/mm	0.0±0.3	0.0±0.6	0.96
Necrotic core
Baseline, mm3/mm	0.1 (0.0, 0.4)	0.1 (0.0, 0.4)	0.63
Follow-up, mm3/mm	0.3 (0.0, 1.1)	0.3 (0.0, 0.9)	0.96
Change from baseline, mm3/mm	0.3±0.6‡	0.3±0.6‡	0.92
Dense calcium
Baseline, mm3/mm	0.0 (0.0, 0.1)	0.0 (0.0, 0.2)	0.12
Follow-up, mm3/mm	0.0 (0.0, 0.3)	0.0 (0.0, 0.4)	0.89
Change from baseline, mm3/mm	0.2±0.4‡	0.1±0.3‡	0.25

Data are expressed as mean±SD, or median (interquartile range).

^*P<0.05

^†P<0.01

^‡P<0.001 vs. baseline.

CNI indicates calcineurin inhibitors; and IVUS, intravascular ultrasound.