Figure 2. Activity with age in 3 min intervals in the 15 min Open Field test.

Horizontal, vertical and fine activity as well as total activity in the center of the arena, of mice at 6, 12, 16 and 20 months old. These results come from the experiments shown in Figure 1 but expressed in 3 min intervals. Data are means ± SEM. *p<0.05, **p<0.01, ***p<0.001, with Welch’s t test within two values of the graph, MANOVA test analysis with “genotype” and “intervals” as factors when considering the genotype effect.