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. Author manuscript; available in PMC: 2013 Jul 30.
Published in final edited form as: Transfus Med Rev. 2013 Jul 8;27(3):137–145. doi: 10.1016/j.tmrv.2013.05.005

Table 3.

Foods, beverages and natural products associated with definite evidence* for the development of drug-induced immune thrombocytopenia [13]

Substance Platelet nadir Bleeding Confirmation
Cow’s milk 5 × 109/L Yes Re-challenge
Cranberry juice 1 × 109/L Yes DDAbs
Jui 0 Yes Re-challenge
Lupinus termis bean 10 × 109/L Not reported Re-challenge
Sesame seeds 6 × 109/L Yes Re-challenge
Walnut (Juglans regia) [46] 4 × 109/L Yes Re-challenge and DDAbs
*

Definite evidence = Ingestion of the substance preceded the thrombocytopenia and platelet count recovered once the substance was stopped; candidate substance was the only agent ingested or other agents were continued or re-introduced and platelet count remained normal; other etiologies of thrombocytopenia were excluded; confirmation in vivo with a re-challenge or in vitro with the demonstration of drug-dependent platelet antibodies (DDAbs).