Vascular niche
|
19797522 |
Lewandowski et al., 2010 |
Vascular endothelial cell (Pecam1+) |
Vascular cell adhesion molecule 1 (Vcam1) |
|
CFSE-labeled CD34-KSL |
|
|
|
15989959 |
Kiel et al., 2005 |
Sinusoidal endothelium (MECA-32+) |
|
|
CD150+CD48-CD41-Lin-
|
|
|
|
17174120 |
Sugiyama et al., 2006 |
CAR cells (Cxcl12+) |
C-X-C motif ligand 12 (Cxcl12) |
C-X-C chemokine receptor type 4 (Cxcr4) |
Sca1+cKit+/CD150+CD48-CD41-
|
CXCL12/CXCR4 signaling |
HSC quiescence |
|
20207228 |
Butler et al., 2010 |
Sinusoidal endothelium (VE-cadherin+) |
Jagged |
Notch |
TNR.GFP+
|
Notch signaling pathway |
|
|
22118468 |
Yamazaki et al., 2011 |
Sinusoidal endothelium (VE-cadherin+) |
|
|
CD150+CD48-CD41-Lin-
|
|
|
|
22281595 |
Ding et al., 2012 |
Sinusoidal endothelium |
Stem cell factor (SCF,Kitl) |
Kit oncogene (c-Kit) |
CD150+CD48-Lin-
|
|
HSC maintenance |
|
22118468 |
Yamazaki et al., 2011 |
Non-myelinated Schwann cell (GFAP+) |
Integrin beta 8 (Itgb8) |
Tgf-beta receptor |
CD150+CD48-CD41-Lin-
|
Tgf-beta/SMAD signaling |
HSC quiescence |
|
20703299 |
Méndez-Ferrer et al., 2010 |
MSC (Nestin+) |
|
|
CD150+CD48-Lin- |
|
HSC homing |
|
22281595 |
Ding et al., 2012 |
Perivascular cell (Lepr+) |
Stem cell factor (SCF,Kitl) |
Kit oncogene (c-Kit) |
CD150+CD48-Lin-
|
|
HSC maintenance |
|
22983360 |
Ludin et al., 2011 |
Monocytes-macrophage (alpha-SMA+) |
Prostaglandin-endoperoxide synthase 2 (Ptgs2, Cox2), C-X-C motif ligand 12 (Cxcl12) |
C-X-C chemokine receptor type 4 (Cxcr4) |
CD150+CD48-CD41-
|
ROS signaling/CXCL12/CXCR4 signaling |
HSC maintenance |
|
21282381 |
Chow et al., 2011 |
Macrophage (CD169+)+MSC (Nes+) |
C-X-C motif ligand 12 (Cxcl12) |
C-X-C chemokine receptor type 4 (Cxcr4) |
CD135-KSL |
CXCL12/CXCR4 signaling |
HSC adhesion/mobilization |
|
21115812 |
de Graaf et al., 2010 |
Megakaryocyte |
Thyroid peroxidase (Tpo) |
Myeloproliferative leukemia virus oncogene (Mpl) |
CD34-CD135-KSL |
TPO/MPL signaling |
|