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. 2013 Jul 30;8(7):e70496. doi: 10.1371/journal.pone.0070496

Figure 1. High expression of Hsp90 in the epidermis of bullous pemphigoid patients.

Figure 1

Hsp90 expression was analyzed in perilesional skin biopsies of bullous pemphigoid (BP) patients and in skin sections of healthy controls by fluorescent immunohistochemistry. (a, b) Representative immunofluorescent and DAPI-counterstained (in blue) skin samples showed a stronger intracellular Hsp90 expression (in green) mainly localized to the epidermal layer of the skin of a BP patient compared to control skin. Magnification: x200. (c, d) Higher magnification (x600) of the respective skin samples. (e) Relative mean epidermal Hsp90 fluorescence intensity by densitometry measurements. Values are mean ± SEM of 6 BP patients and 6 controls. ***P<0.001.