Table 1. Outcomes associated with each risk factor, studies from which RRs were extracted, and procedures for estimating RRs by age group.
| Disease outcome | Studies that reported RRs | Procedures for estimating RRs in standardized age groups |
| Systolic blood pressure (SBP) | ||
| Ischemic heart disease (IHD) | PSC | Interpolation and extrapolation |
| APCSC | Interpolation and extrapolation | |
| Ischaemic stroke | PSC | Interpolation and extrapolation |
| APCSC | Interpolation and extrapolation | |
| Haemorrhagic stroke | PSC | Interpolation and extrapolation |
| APCSC | Interpolation and extrapolation | |
| Hypertensive heart disease | PSC | Redistribution from a single age group using PSC “SBP-other vascular diseases” age pattern |
| APCSC | Interpolation and extrapolation | |
| Rheumatic heart diseasea | PSC | Redistribution from a single age group using PSC SBP-“other vascular diseases” age pattern |
| Inflammatory heart diseasea | PSC | Redistribution from a single age group using PSC “SBP-other vascular diseases” age pattern |
| Aortic aneurysm | PSC | Redistribution from a single age group using PSC “SBP-other vascular diseases” age pattern |
| All other cardiovascular diseasesb | PSC | Redistribution from a single age group using PSC “SBP-other vascular diseases” age pattern |
| APCSC | Redistribution from a single age group using PSC “SBP-other vascular diseases” age pattern | |
| Total cholesterol (TC) | ||
| IHD | PSCc | Interpolation and extrapolation |
| APCSC | Data provided in GBD age groups | |
| Ischemic stroke | PSC | Interpolation and extrapolation |
| APCSC | Data provided in GBD age groups | |
| Fasting plasma glucose (FPG) | ||
| IHD | DECODE | Interpolation and extrapolation |
| APCSC | Interpolation and extrapolation | |
| ERFC | Interpolation and extrapolation. | |
| Total stroke | DECODE | Interpolation and extrapolation |
| APCSC | Interpolation and extrapolation | |
| ERFC | Interpolation and extrapolation | |
| Body mass index (BMI) | ||
| IHD | PSC | Interpolation and extrapolation |
| APCSC | Interpolation and extrapolation | |
| ERFC | Interpolation and extrapolation | |
| Ischaemic stroke | PSC | Redistribution from a single age group using PSC BMI-total stroke age pattern |
| APCSC | Interpolation and extrapolation | |
| ERFC | Interpolation and extrapolation | |
| Haemorrhagic stroke | PSC | Redistribution from a single age group using PSC BMI-total stroke age pattern |
| ERFC | Interpolation and extrapolation | |
| Diabetes | PSC | Interpolation and extrapolation |
| APCSC | Interpolation and extrapolation | |
a
RRs apply to mortality but not to incidence and is included because of the benefits of lower blood pressure for reduced heart failure mortality.
b
This residual category contains a number of ICD codes. The proportion of deaths from the constituent diseases is likely to vary across world regions and even across cohorts in the same meta-analysis.
c
A quadratic age model was used instead of a log-linear age model as this fit the data better.