Table 1. The numbers of Iba1+ and GFP+ cells around the injured sciatic nerve.
Contralateral | Ipsilateral | |||||||
TRPM2BM+/Rec+ | TRPM2BM–/Rec+ | TRPM2BM+/Rec– | TRPM2BM–/Rec– | TRPM2BM+/Rec+ | TRPM2BM–/Rec+ | TRPM2BM+/Rec– | TRPM2BM–/Rec– | |
Total cells | 3.7 ± 0.7 | 4.3 ± 1.3 | 3.0 ± 0.6 | 3.4 ± 0.8 | 24.7 ± 7.3 | 25.0 ± 0.6 | 32.0 ± 4.6 | 20.6 ± 3.0 |
Iba1+ cells | 0.7 ± 0.3 | 1.3 ± 0.6 | 1.0 ± 0.6 | 1.2 ± 0.6 | 18.7 ± 7.3 | 15.7 ± 3.7 | 17.0 ± 6.1 | 11.2 ± 3.6 |
GFP+ cells | 3.3 ± 0.9 | 4.0 ± 1.5 | 3.0 ± 0.6 | 3.2 ± 0.7 | 18.7 ± 4.3 | 23.3 ± 1.8 | 32.0 ± 4.6 | 19.6 ± 2.8 |
Iba1–/GFP+ cells | 3.0 ± 0.6 | 3.0 ± 1.2 | 2.0 ± 0.6 | 2.2 ± 0.9 | 6.0 ± 2.0 | 9.3 ± 3.7 | 15.0 ± 2.5 | 9.4 ± 2.7 |
Iba1+/GFP– cells | 0.3 ± 0.3 | 0.3 ± 0.3 | 0 | 0.2 ± 0.2 | 6.0 ± 3.2 | 1.7 ± 1.7 | 0 | 1.0 ± 1.0 |
Iba1+/GFP+ cells | 0.3 ± 0.3 | 1.0 ± 0.6 | 1.0 ± 0.6 | 1.0 ± 0.5 | 12.7 ± 4.1 | 14.0 ± 2.0 | 17.0 ± 6.1 | 10.2 ± 3.3 |
The numbers of Iba1+ cells, GFP+ cells, Iba1+/GFP– cells, Iba1–/GFP+ cells, and Iba1+/GFP+ cells were counted in the contralateral and ipsilateral sciatic nerve 14 days after pSNL surgery. “Total cells” indicates the sum of Iba1+/GFP– cells, Iba1–/GFP+ cells, and Iba1+/GFP+ cells. n = 3–5. Data are expressed as mean ± SEM.