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. 2013 Jul 30;8(7):e69239. doi: 10.1371/journal.pone.0069239

Figure 2. Exposure of prostate cancer cell lines to hypoxia induces production and release of miR-210 into the extracellular environment.

Figure 2

Left column, miR-210 copies/ng RNA in LNCaP and VCaP human prostate cancer cell lines cultured in normoxic (20% O2) (white bars) or hypoxic (1% O2) (blue bars) conditions for 24, 48 or 72 hours. Right column, miR-210 copies/µl in filtered conditioned media corresponding to cellular samples. *, P value <0.05; **, P value <0.01; ***, P value <0.001 (Student’s t-test).