Table 1. Evaluation of potency and cytotoxicity of the selected compounds in cell assays.
EC50 (µM)a | CC50 (µM)b | CC50/EC50 | |
Compound 1 | 0.03 | >120 | >4000 |
Compound 2 | 10 | 80 | 8 |
Compound 3 | 0.03 | 8 | 240 |
Compound 5 | 60 | >120 | >2 |
Compound 6 | 20 | >120 | >6 |
Compound 7 | 2 | >120 | >60 |
Compound 8 | 4 | 60 | 15 |
EC50, effective concentration 50%;
CC50, cytotoxic concentration 50%.
Relative error in the parameters is 15%.