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. 2013 Jul 30;8(7):e70096. doi: 10.1371/journal.pone.0070096

Table 1. Overlapping decreased expression changes relative to control induced by SRC-2 KD and cAMP in MCF-7 cells.

Signal intensity FC
Gene Definition SRC-2 shRNA cAMP CtrshRNA SRC-2 shRNA/Ctr shRNA cAMP/Ctr shRNA
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 255 257 507 −1.98 −1.98
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 420 415 632 −1.50 −1.53
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein),transcript variant 1 232 313 570 −2.46 −1.83
CAV1 caveolin 1, caveolae protein, 22kDa 3534 2946 5595 −1.59 −1.91
EGR1 early growth response 1 1159 1125 1799 −1.55 −1.62
KLK5 kallikrein-related peptidase 5, transcript variant 1 345 292 598 −1.74 −2.06
KLK5 kallikrein-related peptidase 5, transcript variant 2 244 226 416 −1.72 −1.84
KRT1 keratin 1 (epidermolytic hyperkeratosis) 143 118 229 −1.60 −1.94
KRT5 keratin 5 171 197 347 −2.03 −1.76
KRTDAP keratinocyte differentiation-associated protein 173 283 571 −3.29 −2.02
Protein S100-A9 S100 calcium binding protein A9 (calgranulin B) 308 644 1345 −4.37 −2.11
Protein S100-A8 S100 calcium binding protein A8 242 530 1892 −7.82 −3.58
TAGLN transgelin, transcript variant 2 257 350 797 −3.10 −2.28

Genes with FC ≥1.5 and q-value = 0 are shown in addition to their respective expression signals in the three microarray samples. cAMP, short-hairpin control MCF-7 cells treated with cAMP analogue (8-CPT-cAMP) and cAMP-elevating agents (IBMX and forskolin).