Table 2. Detection of drug-resistance mutations in treatment naive patients by PASS.

Patient	Genotype	VL (Log10 IU/ml)	HBeAg	No. of analyzed genomes	% of viruses with mutations	No. of mutations	No. of linkages
N047	C	8.0	+	2,772	0.44	4	1
N048	C	7.4	+	1,616	0.19	4	1
N049	B	7.9	+	1,010	0.20	3	1
N050	B	7.7	+	644	0.31	3	1
N051	C	7.7	+	327	0.62	4	1
N052	C	7.8	+	2,107	0.29	4	1
N053	D	7.6	+	1,120	0.27	2	0
N054	B	7.2	+	2,223	0.09	1	0
N055	C	7.2	+	317	0.00	0	0
N056	B	7.6	+	444	0.23	1	0
N057	C	6.9	+	2,352	0.38	1	0
N058	C	6.6	+	1,269	0.16	2	0
N059	C	7.7	+	1,179	0.00	0	0
N060	B	7.6	+	1,141	0.00	0	0
N061	C	6.0	+	826	0.24	1	0
N062	B	7.9	+	921	0.11	1	0
N063	C	5.8	+	1,303	3.15	4	5
N064	C	5.5	+	1,821	0.16	2	0
N065	C	8.2	+	1,159	0.35	1	0
N066	C	6.1	+	1,323	1.14	2	1
N067	C	7.7	+	638	0.32	2	0
N068	C	7.9	+	1,743	0.12	2	0
N069	C	7.7	+	1,302	0.08	1	0
N070	C	6.2	−	1,625	0.55	2	1
N071	C	7.0	+	449	3.79	3	2
N072	B	6.3	+	1,407	0.43	2	0
N073	C	5.5	+	1,386	0.29	1	0
N074	B	8.0	+	1,520	0.00	0	0
N075	C	7.9	+	881	0.00	0	0
Mean		7.2 (5.5–8.0)		1,257 (317–2,772)	0.32 (0.09–3.79)	1.8 (0–4)	1.3 (0–5)