Table 2. Detection of drug-resistance mutations in treatment naive patients by PASS.
Patient | Genotype | VL (Log10 IU/ml) | HBeAg | No. of analyzed genomes | % of viruses with mutations | No. of mutations | No. of linkages |
N047 | C | 8.0 | + | 2,772 | 0.44 | 4 | 1 |
N048 | C | 7.4 | + | 1,616 | 0.19 | 4 | 1 |
N049 | B | 7.9 | + | 1,010 | 0.20 | 3 | 1 |
N050 | B | 7.7 | + | 644 | 0.31 | 3 | 1 |
N051 | C | 7.7 | + | 327 | 0.62 | 4 | 1 |
N052 | C | 7.8 | + | 2,107 | 0.29 | 4 | 1 |
N053 | D | 7.6 | + | 1,120 | 0.27 | 2 | 0 |
N054 | B | 7.2 | + | 2,223 | 0.09 | 1 | 0 |
N055 | C | 7.2 | + | 317 | 0.00 | 0 | 0 |
N056 | B | 7.6 | + | 444 | 0.23 | 1 | 0 |
N057 | C | 6.9 | + | 2,352 | 0.38 | 1 | 0 |
N058 | C | 6.6 | + | 1,269 | 0.16 | 2 | 0 |
N059 | C | 7.7 | + | 1,179 | 0.00 | 0 | 0 |
N060 | B | 7.6 | + | 1,141 | 0.00 | 0 | 0 |
N061 | C | 6.0 | + | 826 | 0.24 | 1 | 0 |
N062 | B | 7.9 | + | 921 | 0.11 | 1 | 0 |
N063 | C | 5.8 | + | 1,303 | 3.15 | 4 | 5 |
N064 | C | 5.5 | + | 1,821 | 0.16 | 2 | 0 |
N065 | C | 8.2 | + | 1,159 | 0.35 | 1 | 0 |
N066 | C | 6.1 | + | 1,323 | 1.14 | 2 | 1 |
N067 | C | 7.7 | + | 638 | 0.32 | 2 | 0 |
N068 | C | 7.9 | + | 1,743 | 0.12 | 2 | 0 |
N069 | C | 7.7 | + | 1,302 | 0.08 | 1 | 0 |
N070 | C | 6.2 | − | 1,625 | 0.55 | 2 | 1 |
N071 | C | 7.0 | + | 449 | 3.79 | 3 | 2 |
N072 | B | 6.3 | + | 1,407 | 0.43 | 2 | 0 |
N073 | C | 5.5 | + | 1,386 | 0.29 | 1 | 0 |
N074 | B | 8.0 | + | 1,520 | 0.00 | 0 | 0 |
N075 | C | 7.9 | + | 881 | 0.00 | 0 | 0 |
Mean | 7.2 (5.5–8.0) | 1,257 (317–2,772) | 0.32 (0.09–3.79) | 1.8 (0–4) | 1.3 (0–5) |