Skip to main content
. Author manuscript; available in PMC: 2013 Jul 31.
Published in final edited form as: Life Sci. 2012 Jun 19;91(0):634–637. doi: 10.1016/j.lfs.2012.06.007

Figure 2. ET-1 exposure increases albumin reabsorption by proximal tubule (PT) segments in ET-1 treated rats.

Figure 2

Representative images of proximal tubule (PT) segments from Munich Wistar Frömter rats observed via 2-photon intravital microscopy before (panel A) and after (panel B) ET-1 treatment. Images taken before ET-1 exposure show some heterogenous accumulation of filtered albumin in PT segments; with some segments exhibiting decreased accumulation (PT*). In images taken after ET-1 infusion, accumulation of albumin was seen in a greater percentage of PT segments, with the number of PT segments showing little or no albumin accumulation (although still present) decreasing in number. Average pixel intensity values for background-subtracted images for individual rats before and after ET-1 treatment in are presented in panel C. (Bar=15μm).