Table 1.
Summary of the effects of baseline characteristics on HRS reversal and survival (univariate analysis, ITT population).
| Baseline parameter | HRS Reversal
|
Survival
|
||||
|---|---|---|---|---|---|---|
| RR | 95% CI | p value | RR | 95% CI | p value | |
| Treatment group | 2.71 | 1.24–5.94 | 0.009 | 0.93 | 0.58–1.51 | 0.782 |
|
| ||||||
| Alcoholic hepatitis | 0.97 | 0.49–1.92 | 0.890 | 2.29 | 1.41–3.72 | <0.001 |
|
| ||||||
| Gender | 0.57 | 0.31–1.08 | 0.055 | 1.00 | 0.59–1.69 | 0.963 |
|
| ||||||
| MELD score | 0.95 | 0.91–0.99 | 0.017 | 1.05 | 1.01–1.10 | 0.030 |
|
| ||||||
| Child-Pugh score | 0.87 | 0.75–1.02 | 0.065 | 1.15 | 1.00–1.32 | 0.051 |
|
| ||||||
| Serum creatinine | 0.65 | 0.46–0.93 | 0.021 | 1.40 | 1.22–1.60 | <0.001 |
|
| ||||||
| Bilirubin | 1.00 | 0.97–1.02 | 0.805 | 1.01 | 1.00–1.03 | 0.087 |
|
| ||||||
| MAP | 0.99 | 0.96–1.02 | 0.459 | 1.02 | 0.99–1.04 | 0.216 |
|
| ||||||
| Serum sodium | 0.99 | 0.95–1.04 | 0.730 | 0.99 | 0.95–1.03 | 0.519 |
RR: relative risk; 95% CI: 95% confidence intervals.