Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Jul 31;33(31):12670–12678. doi: 10.1523/JNEUROSCI.1086-13.2013

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 the authors 0270-6474/13/3312670-09$15.00/0

PMC Copyright notice

Figure 6. — Reduced induction and normal expression of mGluR-LTD in AI rats. A, Bath application of the type I mGluR agonist DHPG (10 min, gray bar) induces LTD in a dose-dependent manner. B, DHPG at a saturating dose (50 μm) induced robust LTD in all age groups. C, The mGluR5 receptor allosteric agonist CDPPB (10 μm) enables the induction of LTD with a subthreshold application of DHPG (10 μm). D, Dose–response relationship of the facilitatory effects of CDPPB on LTD induced with 10 μm DHPG. LTD was quantified 60 min after DHPG washed out. E, CDPPB promotes the induction of mGluR-LTD induced with ppLFS in the presence of APV in AI rats. F, The facilitation of mGluR-LTD (ppLFS with APV) measured in the three groups (control, white bars; with CDPPB, black bars). The number of slices and rats is indicated in each part; *p < 0.005.