Figure 4.

Orientation selectivity in the dLGN does not require cortical feedback. A, The dLGN receives feedforward input from the retina, and feedback input directly and indirectly from the cortex. B, Injection of muscimol solution completely abolished VEPs at different depths in V1. C, Responses before (red) and after (blue) muscimol injection in an example cell. D, Normalized responses before (red) and after (blue) muscimol injection (n = 8). All responses were normalized by the peak response before injection, and the preferred direction of each cell was aligned. E, F, OSI and TW before and after muscimol injection (n = 8, p = 0.22 for OSI and n = 0.99 for TW, paired t test).