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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Hypertension. 2012 Dec 10;61(2):327–332. doi: 10.1161/HYPERTENSIONAHA.112.193631

Figure 2. Comparison of wild-type and corin-Tg mice.

Figure 2

(A) Corin-Tg and wild-type female littermates and hearts are similar in appearance (15 weeks old, bar=2 mm). (B) Corin protein expression is increased in the heart of corin-Tg mice (female, 15 week old) assessed by Western blotting under reducing conditions with anti-corin antibodies (upper panel). Quantitation of corin expression (vs. Glut-4 expression, n=4 each group). (C) Survival in lines of corin-Tg mice and wild-type mice is similar (n=701). (D) Comparison of body weight (B), heart weight (H) and B:H values between corin-Tg and wild-type mice littermates (n=11-20 in each group; female data is shown). (E) Similar systolic (SBP), diastolic (DBP) or mean arterial blood pressure (MAP) in corin-Tg (n = 5 females, 15 males) and wild-type (n = 6 females, 16 males) mice.