A Family-Based Probabilistic Method for Capturing De Novo Mutations from High-Throughput Short-Read Sequencing Data

. Author manuscript; available in PMC: 2013 Jul 31.

Published in final edited form as: Stat Appl Genet Mol Biol. 2012 Jan 6;11(2):10.2202/1544-6115.1713 /j/sagmb.2012.11.issue-2/1544-6115.1713/1544-6115.1713.xml. doi: 10.2202/1544-6115.1713

θ	the per-site, population diversity parameter; θ = 4N_eμ
μ	the per-site, per-generation germline mutation rate
μ_s	the per-site somatic mutation rate
ε	the per-site sequencing error rate