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Correlation between Nrf2 and tissue-specific expression patterns of phase II and phase III enzymes
| Kidney | Intestine | Lung | |
|---|---|---|---|
| A. Changes owing to castration | |||
| Nrf2 | ↑ | ↑ | — |
| Sult | ↑ | ↑ | — |
| Ugt1a | ↑ | ↑ | —/↑ |
| Ugt2b | ↓ | ↓ | — |
| Mrp | ↑ | ↑ | — |
| B. Changes owing to the loss of Mrp1 | |||
| Nrf2 | — | ↓ | ↓ |
| Sult | — | — | ↓ |
| Ugt1a | —/↓ | — | ↓ |
| Ugt2b | — | — | ↓ |
| Mrp | —/↓ | — | ↓ |
