Figure 2.

Influence of different concentrates on platelet interactions using the cone and platelet technology.

Bar diagrams indicate the percentage of surface covered by platelets with whole blood (Con), after 30% haemodilution using Ringer’s lactate (RL), and after in vitro addition of fibrinogen (Fbn) at 2 mg/mL, prothrombin complex concentrates (PCC) at 35 IU/kg, activated recombinant factor VII (rFVIIa) at 6 μg/mL, and cryoprecipitates (cryo) at a dose of 2 cryo/10 kg of weight. Panel A shows the total percentage of surface covered (SC) by platelets and panel B shows the average size (AS) of the aggregates formed, expressed in μm². Results are expressed as mean ± SEM, n=8 (*P <0.05 vs whole blood).