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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Clin Pharmacol Ther. 2012 Nov 14;92(6):771–777. doi: 10.1038/clpt.2012.186

Figure 2. CYP2B6 genotype groups alter hydroxybupropion formation.

Figure 2

Association of CYP2B6 genotype groups with left: hydroxybupropion/bupropion ratios and middle: hydroxybupropion levels in bupropion adherent individuals (n=154, slow: n=31, intermediate: n=64, normal: n=58). Right: CYP2B6 genotype-based predicted dose adjustment to 700 ng/ml hydroxybupropion. OH-BUP=hydroxybupropion, and BUP=Bupropion.