Fig. 7. NCRs downregulation occurs following both direct and indirect-NCR activation of NK cells.
The whisker box plots depict changes in both NKp46 (A and B) and NKp30 (C and D) expression on NK cells following direct stimulation with the NCR-ligand expressing cell line 221, or the non-NCR-ligand expressing cell line K562. (A and C) The percentages of NKp46+ and NKp30+ NK cells; (B and D) The mean fluorescence intensity of each NCR on NK cells differences where p < 0.05 is indicated.