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. Author manuscript; available in PMC: 2013 Jul 31.
Published in final edited form as: Cochrane Database Syst Rev. 2009 Oct 7;(4):CD006126. doi: 10.1002/14651858.CD006126.pub2

Characteristics of ongoing studies

HSO Study
Study name The Heavy Silicone Oil versus Standard Silicone Oil Study (HSO)
Methods Randomized controlled trial to determine safety and efficacy of vitrectomy with two types of endotamponades
Participants Multicenter study enrolling patients with inferior and posterior PVR grade C-A6, P12 according to Machemer or inferior detachment with giant retinal tear in the inferior hemisphere
Interventions Two-arm parallel group design:

  1. Heavy silicone oil (endotamponade with heavy silicone oil)

  2. Standard silicone oil (endotamponade with silicone oil of viscosity: 1000 or 5000 cSt)
Outcomes Main endpoints: Complete retinal attachment at 12 months and change of visual acuity at 12 months postoperatively
Secondary endpoints: Complete retinal attachment before endotamponade removal, quality of life analysis, and the evaluation of the number of retina affecting re-operation within 1 year of follow-up
Other endpoints: Emulsification of the compound, cataract formation, number of eyes with constantly raised intraocular pressure from baseline, and the number of eyes with glaucoma
Starting date January 2004
Contact information Antonia M Joussen, Department of Ophthalmology, University of Düsseldorf, Moorenstrasse 5, Düsseldorf, Germany;
Notes The present article describes the methods and design. The investigators have not published results.