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. Author manuscript; available in PMC: 2014 Jan 2.
Published in final edited form as: Angew Chem Int Ed Engl. 2012 Oct 24;52(1):331–335. doi: 10.1002/anie.201205474

Figure 1.

Figure 1

Micro-coil pulsed field gradient-stimulated echo (PFG-STE) NMR measurements of translational diffusion coefficients, Dt, of the β2AR-T4L–timolol complex in aqueous DDM solutions, pH = 7.5, T = 298K. Measurements of Dt performed at discrete DDM concentrations are plotted versus the DDM concentration. (A) 0.5 mM β2AR-T4L–timolol complex reconstituted in DDM micelles. (■) Dt,pm obtained from direct 1H NMR observation of the protein (◆) Dt,pmapp obtained from 1H NMR observation of DDM. The straight line represents a regression of the Dt,pm values. (B) 0.5 mM β2AR-T4L–timolol complex reconstituted in DDM micelles containing CHS at a CHS:DDM ratio of 0.2. Same presentation as in (A).