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. 2013 Jul 30;54(7):5136–5143. doi: 10.1167/iovs.13-12337

Table 1.

Nucleic Acid Constructs

Construct
Mechanism
Purpose
Attributes
Source
Aqp0a-MO Morpholino injection Knockdown Synthetic (GeneTools)
Aqp0b-MO Morpholino injection Knockdown Synthetic (GeneTools)
Aqp0a Transgenic expression Self/cross-rescue Zebrafish (D. rerio)
Aqp0aN8Q Transgenic expression Rescue experiment No permeability Zebrafish (D. rerio)
Aqp0b Transgenic expression Self/cross-rescue Zebrafish (D. rerio)
MIPfun Transgenic expression Rescue experiment Killifish (F. heteroclitus)
MIPfunN68Q Transgenic expression Rescue experiment No permeability Killifish (F. heteroclitus)
MIPfunS231A Transgenic expression Rescue experiment Unphosphorylatable Killifish (F. heteroclitus)
MIPfunS231D Transgenic expression Rescue experiment Phosphomimetic Killifish (F. heteroclitus)
MIPfunY75G Transgenic expression Rescue experiment No calcium regulation Killifish (F. heteroclitus)
AQP1 Transgenic expression Rescue experiment Human (Homo sapiens sapiens)
AQP0 Transgenic expression Rescue experiment Bovine (Bos taurus)