Bone mineralization, crystallinity and collagen cross-linking were assessed in the femora by FTIRI in (A) cortical compartment of the diaphysis of Cx43fl/− and OCN-Cre;Cx43fl/− mice and (B) cancellous compartment of distal femora and cortical compartment of the diaphysis of Cx43fl/fl and DMP1-8kb-Cre;Cx43fl/fl mice. Ct: cortical, Cn: cancellous. Bars are mean ± SD. *, p<0.05 by independent Mann Whitney u-tests, n= 3. (C) Bone material density was measured by μCT in the femoral midshaft. Bars are mean ± SD, n=7-10.