Table 1. Relative mRNA Expression Level in Colon Tissues.

	Genes	IL-10−/−	IFN-αβR−/−	IL-10−/−IFN-αβR−/−
Cytokines	IL1β	1.0 ± 0.1	1.8 ± 0.6	33.8 ± 8.7a
	IL-17	1.0 ± 0.2	1.1 ± 0.2	3.3 ± 1.3
	GM-CSF	1.0 ± 0.4	1.2 ± 0.5	5.4 ± 2.0
	IFNγ	1.0 ± 0.2	0.6 ± 0.2	23.6 ± 0.1b
	TNFα	1.0 ± 0.2	0.7 ± 0.2	9.0 ± 1.3b
Cell markers	CD3d	1.0 ± 0.2	1.2 ± 0.3	11.6 ± 2.1b
	F4/80	1.0 ± 0.2	0.6 ± 0.1	2.9 ± 0.7
Chemokines	KC	1.0 ± 0.2	1.8 ± 0.9	67.3 ± 12.5b
	MIP1α	1.0 ± 0.1	0.4 ± 0.1b	3.7 ± 0.9a
	MIP1β	1.0 ± 0.2	2.4 ± 0.3a	25.8 ± 8.7a
	CXCL10	1.0± 0.2	2.6 ± 0.6	33.1 ± 17.9
	CCL22	1.0 ± 0.1	0.4 ± 0.2a	8.4 ± 2.9

NOTE. Total RNA was isolated from the distal colon tissue, and mRNA expression levels were measured by qRT-PCR for the indicated genes in 17-week-old IL-10^−/−, IFN-αβR^−/−, and IL-10^−/−IFN-αβR^−/− mice (n = 4 each) was measured by qPCR. The data represent 3–4 mice per group. Significant differences were calculated in comparison with the IL-10^−/− mice.

^aP < .05.

^bP < .01.