Table 3.
Multivariate Cox regression analysis of disease-specific survivala
| Characteristics | HR (95% CI) | P value |
|---|---|---|
| Vessel involvement |
|
0.667 |
| No |
1.000 |
|
| Yes |
0.868 (0.456 to 1.652) |
|
| Perineural invasion |
|
0.205 |
| No |
1.000 |
|
| Yes |
1.555 (0.786 to 3.075) |
|
| Tumor grade |
|
0.003 |
| T1 |
1.000 |
|
| T2 |
2.177 (0.474 to 6.841) |
0.198 |
| T3 |
4.190 (0.733 to 10.148) |
0.090 |
| T4 |
7.170 (1.909 to 15.503) |
0.010 |
| N stage |
|
<0.001 |
| N0 |
1.000 |
|
| N1 |
1.315 (0.709 to 2.440) |
0.385 |
| N2 |
2.366 (1.143 to 4.897) |
0.020 |
| N3 |
16.474 (6.390 to 42.468) |
<0.001 |
| MLNR stage |
|
<0.001 |
| MLNR0 |
1.000 |
|
| MLNR1 |
1.173 (0.625 to 2.203) |
0.619 |
| MLNR2 |
2.678 (1.320 to 5.433) |
0.006 |
| MLNR3 | 7.860 (3.695 to 16.718) | <0.001 |
aCI, confidence interval; HR, hazard ratio.