Figure 2.
Schematic representation of T cell subsets in allergic disease. Naive T cells are induced to differentiate into diverse lineages which can be defined based on characteristic transcription factors, surface markers, effector cytokines, and other surrogate markers. As stated in their respective boxes, each of the lineages depicted here (TH1, multiple TH2 subsets, TH9, TH17, TH22, Treg, and TFH) have a demonstrated role in either promoting or suppressing allergic disease.