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. 2013 Jul 6;14:61. doi: 10.1186/1471-2156-14-61

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Copyright © 2013 Aigner et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Differential expression of genes depending on BTNL8/BTNL3 genotype. (A) Nine genes could be confirmed by RT-qPCR analysis to be differentially expressed in LCLs homozygous for the BTNL8_BTNL3-del allele. Red, increased mRNA level; green, decreased mRNA level in LCLs homozygous for the CNV. (B) Network of genes formed by Ingenuity Pathway Analysis. Genes depicted in red (increased mRNA level) and green (decreased mRNA level) were confirmed by RT-qPCR analysis to be differentially expressed in LCLs homozygous for the CNV. Genes depicted in white were not found to be deregulated even though they are part of the same network.