Table 1.
Association between SNAT1 and p-Akt expression and clinicopathologic factors in breast cancer
| Clinicopathological variables | N (%) |
SNAT1 (%) |
P |
p-Akt (%) |
P | |||
|---|---|---|---|---|---|---|---|---|
| Positive | Negative | Positive | Negative | |||||
| Age(y) |
|
|
|
|
|
|
|
|
| |
<50 y |
96(45.7) |
58(60.4) |
38(39.6) |
0.987 |
64(66.7) |
32(33.3) |
0.509 |
| |
≥50 y |
114(54.3) |
69(60.5) |
45(39.5) |
|
71(62.3) |
43(37.7) |
|
| pT |
|
|
|
|
|
|
|
|
| |
pT1/2 |
174(82.9) |
93(53.4) |
81(46.6) |
<0.001 |
104(59.8) |
70(40.2) |
0.003 |
| |
pT3/4 |
36(17.1) |
34(94.4) |
2(5.6) |
|
31(86.1) |
5(13.9) |
|
| pN |
|
|
|
|
|
|
|
|
| |
No |
136(64.8) |
58(42.6) |
78(57.4) |
<0.001 |
64(47.1) |
72(52.9) |
<0.001 |
| |
Yes |
74(35.2) |
69(93.2) |
5(6.8) |
|
71(95.9) |
3(4.1) |
|
| Disease stage |
|
|
|
|
|
|
|
|
| |
I/II |
168(80.0) |
85(50.6) |
83(49.4) |
<0.001 |
96(57.1) |
72(42.9) |
<0.001 |
| |
III/IV |
42(20.0) |
42(97.6) |
1(2.4) |
|
39(92.9) |
3(7.1) |
|
| Her2 |
|
|
|
|
|
|
|
|
| |
+ |
53(25.2) |
32(60.4) |
21(39.6) |
0.986 |
37(69.8) |
16(30.2) |
0.332 |
| |
- |
157(74.8) |
95(60.5) |
62(39.5) |
|
98(62.4) |
59(37.6) |
|
| Ki67 |
|
|
|
|
|
|
|
|
| |
+ |
166(79.0) |
109(65.7) |
57(34.3) |
0.003 |
112(67.5) |
54(32.5) |
0.061 |
| |
- |
44(21.0) |
18(40.9) |
26(59.1) |
|
23(52.3) |
21(47.7) |
|
| ER |
|
|
|
|
|
|
|
|
| |
+ |
117(55.7) |
60(47.2) |
57(48.7) |
0.002 |
67(57.3) |
50(42.7) |
0.017 |
| |
- |
93(44.3) |
67(72.0) |
26(28.0) |
|
68(73.1) |
25(26.9) |
|
| PR |
|
|
|
|
|
|
|
|
| |
+ |
105(50.0) |
60(57.1) |
45(42.9) |
0.323 |
70(66.7) |
35(33.3) |
0.471 |
| |
- |
105(50.0) |
67(63.8) |
38(36.2) |
|
65(61.9) |
40(38.1) |
|
| Total | 210 | 127(60.5) | 83(39.5) | 135(64.3) | 75(35.7) | |||