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MLH1 foci are formed in a fraction of Spo11Gal/Galoocytes. Chromosomal spreads from E18.5 ovaries were immunostained with antibodies to MLH1 (red) and SCP3 (green). Note incomplete synapsis and consequent reduction in the number of MLH1 foci in Spo11Gal/Gal oocytes.
