Table 1. Characteristics of patients with invasive breast cancer (ICD-10: C50) diagnosed in Saarland in 2000-2009.
| Characteristic | Category | 2000-2004 |
2005-2009 |
||
|---|---|---|---|---|---|
| n | % | n | % | ||
| Overall | 4147 | 4424 | |||
| Age | 15-49 | 754 | 18.2 | 785 | 17.7 |
| 50-69 | 1973 | 47.6 | 2098 | 47.4 | |
| > = 70 | 1420 | 34.2 | 1541 | 34.8 | |
| Stage | available | 3574 | 86.2 | 3642 | 82.3 |
| localizeda | 1817 | 50.8 | 1823 | 50.1 | |
| regionally/locally advanceda | 1424 | 39.8 | 1519 | 41.7 | |
| distanta | 333 | 9.3 | 300 | 8.2 | |
| Microscopic confirmation | 4031 | 97.2 | 4312 | 97.5 | |
| Morphology | available | 4031 | 97.2 | 4305 | 97.3 |
| invasive ductala | 2710 | 67.2 | 3041 | 70.7 | |
| invasive lobulara | 563 | 14.0 | 656 | 15.2 | |
| mixed typea | 352 | 8.7 | 279 | 6.5 | |
| othera,b | 406 | 10.1 | 329 | 7.6 | |
| Grading | available | 3856 | 93.0 | 4201 | 95.0 |
| lowa | 277 | 7.2 | 304 | 7.2 | |
| intermediatea | 2273 | 58.9 | 2872 | 68.4 | |
| higha | 1306 | 33.9 | 1025 | 24.4 | |
| Hormone receptor status | available | 3620 | 87.3 | 3720 | 84.1 |
| positive (ER+ PgR+)a | 2474 | 68.3 | 2688 | 72.3 | |
| mixed (ER+ or PgR+)a | 531 | 14.7 | 451 | 12.1 | |
| negative (ER-PgR-)a | 615 | 17.0 | 581 | 15.6 | |
| HER2/neu | available | 2505 | 60.4 | 3598 | 81.3 |
| positivea,c | 625 | 25.0 | 866 | 24.1 | |
| negativea | 1880 | 75.0 | 2732 | 75.9 | |
| Death certificate only notified | 67 | 1.6 | 100 | 2.3 | |
| No follow-up available | 79 | 1.9 | 48 | 1.1 | |
NB: ER = estrogen receptor; PgR = progesterone receptor; a proportions among patients with available information; b including mucinous (195) and tubular (109) carcinoma, M. Paget (57), inflammatory carcinoma (14), other specified (253) and non-specified (107) carcinoma; c including 401 tumors with borderline expression