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The suggested strategy for patients belonging to this group is single ASCT in patients chemosensitive to salvage therapy. For patients who achieve chemosensitivity only after ≥ third-line salvage chemotherapy, tandem ASCT could be considered. Consolidation RT could be considered after transplantation in selected indications. HTD: high-dose therapy; ASCT: autologous stem cell transplantation; RT: radiotherapy.
