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. 2013 Aug 1;7:424. doi: 10.3389/fnhum.2013.00424

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Copyright © 2013 Lewitus, Kelava and Huttner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic of neural progenitors in the developing neocortex in mouse (left) and human (right). Polarized progenitors (bRG and aRG) are depicted with processes extending to the apical (bottom) and/or basal (top) surface. Non-polarized cells (IPCs and TAPs) divide exclusively in the SVZ in both mouse and human. The human SVZ is relatively expanded compared to the mouse and divided into an outer (OSVZ) and inner (ISVZ) region. CP, cortical plate; IZ, intermediate zone; MZ, marginal zone; SP, subplate.