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. 2013 Aug 1;6(4):458–469. doi: 10.1593/tlo.13238

Figure 2.

Figure 2

Fold change of RECQ helicase mRNA expression (CRC/normal colon). Solid horizontal lines indicate the median fold change for each RECQ helicase. The dashed horizontal line indicates a fold change level of 1, where the expression level of the RECQ helicase in the tumor is equal to the expression level in normal colonic mucosa. BLM and RECQL4 expression is significantly higher in the CRCs compared to the matched normal colon (P = .0011 and P < .0001, respectively). RECQL (P = .0103) and RECQL5 (P = .0029) expression is significantly lower in the primary CRCs compared to the matched normal colon mucosa. There is no significant difference in WRN mRNA expression in tumor compared to normal colonic mucosa. Asterisks indicate statistical significance in the fold change compared to the theoretical mean of 1 for the indicated helicases.