Table 1.

Clinical and Histopathologic Characteristics of the Patients in the Breast Cancer Tissue Microarray.

Effect	Level	Number of Patients	Cancer-Specific Survival			Time to Local Recurrence			Time to Metastasis Formation
			Global P	Events	HR with 95% CI	Global P	Events	HR with 95% CI	Global P	Events	HR with 95% CI
Age at diagnosis	≤50	20	.182	8	(Ref.)	.973	2	(Ref.)	.259	9	(Ref.)
	>50	61		15	0.56 (0.24–1.33)		6	0.97 (0.20–4.83)		21	1.56 (0.71–3.42)
T	1	40	.118	7	(Ref.)	.361	2	(Ref.)	.001	8	(Ref.)
	2	31		12	2.65 (1.04–6.74)		5	3.70 (0.72–19.16)		15	3.36 (1.42–7.97)
	3	8		4	1.99 (0.67–5.91		1	1.39 (0.17–11.64)		6	2.70 (1.08–6.72)
	4	2		0	-		0	-		1	1.58 (0.21–11.69)
N	0	46	.266	9	(Ref.)	.496	4	(Ref.)	< .001	11	(Ref.)
	1	18		9	2.85 (1.13–7.19)		4	3.02 (0.75–12.07)		7	1.88 (0.73–4.86)
	2	6		1	0.50 (0.67–3.75)		0	-		4	2.78 (0.93–8.25)
	3	10		4	1.77 (0.52–6.00)		0	-		7	2.11 (0.88–5.06)
	4	1		0	-		0	-		1	61.50 (3.84–985)
ER	Negative	42	< .001	19	(Ref.)	.027	7	(Ref.)	.033	19	(Ref.)
	Positive	39		4	0.18 (0.06–0.53)		1	0.13 (0.02–1.09)		11	0.45 (0.22–0.96)
PR	Negative	51	.396	16	(Ref.)	.436	6	(Ref.)	.133	22	(Ref.)
	Positive	30		7	0.68 (0.28–1.66)		2	0.56 (0.11–2.65)		8	0.54 (0.24–1.22)
HER2	Negative	63	.585	17	(Ref.)	.833	6	(Ref.)	.276	26	(Ref.)
	Positive	18		6	1.30 (0.51–3.29)		2	1.19 (0.24–5.89)		4	0.56 (0.20–1.61)
Fibronectin score	0	54	.013	13	(Ref.)	.6699	5	(Ref.)	.124	19	(Ref.)
	1	18		5	0.96 (0.31–2.93)		2	1.20 (0.23–6.20)		7	1.31 (0.55–3.11)
	2	9		5	4.61 (1.73–12.31)		1	1.43 (0.17–12.10)		4	1.71 (0.58–5.04)
Fibronectin score	0 + 1	72	< .001	17	(Ref.)	.706	7	(Ref.)	.259	26	(Ref.)
	2	9		6	4.56 (1.79–11.63)		1	1.50 (0.18–12.27)		4	1.83 (0.63–2.30)

T indicates tumor size; N, nodal status; HR, hazard ratio; CI, confidence interval; Ref., reference. Significant P values are bolded.