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. 2013 Aug;15(8):925–938. doi: 10.1593/neo.13762

Table 2.

Clinical and Histopathologic Characteristics of the Patients in the Second Prostate Tissue Microarray.

Effect Level Number of Patients Cancer-Specific Survival Time to Local Recurrence Time to Metastasis Formation



Global P Events HR with 95% CI Global P Events HR with 95% CI Global P Events HR with 95% CI
PSA (ng/ml) ≤4 18 .168 0 (Ref.) .196 3 (Ref.) .335 1 (Ref.)
4–10 33 2 2 x 105 (0 to >1010) 11 2.70 (0.75–9.75 4 2.74 (0.30–24.73)
>10 38 4 664 (0 to >1010) 13 1.56 (0.67–3.61) 6 1.81 (0.47–7.04)
89
T 0 54 .053 2 (Ref.) < .001 11 (Ref.) .001 3 (Ref.)
1 29 4 4.65 (0.84–25.6) 16 4.66 (2.10–10.35) 8 6.88 (1.81–26.14)
N 0 83 .001 4 (Ref.) < .001 24 (Ref.) .002 9 (Ref.)
1 5 2 9.86 (1.79–54.45) 3 6.74 (1.98–22.90) 2 8.03 (1.70–37.96)
Gleason score 0–7a 70 .004 2 (Ref.) .004 17 (Ref.) .003 5 (Ref.)
>7a 19 4 8.02 (1.47–43.84) 10 2.96 (1.36–6.48) 6 5.09 (1.55–16.67)
Resection R0 71 .007 3 (Ref.) .001 18 (Ref.) .015 7 (Ref.)
R1 18 3 7.27 (1.36–38.78) 9 3.68 (1.64–8.26) 4 4.29 (1.21–15.23)
Fibronectin score 0 41 .031 3 (Ref.) .086 11 (Ref.) .004 4 (Ref.)
1 36 0 - 13 1.98 (0.85–4.63) 4 2.48 (0.56–10.99)
2 12 3 3390 (0 to >1010) 3 1.63 (0.49–5.47) 3 6.71 (1.72–26.08)
Fibronectin score 0 + 1 77 < .001 3 (Ref.) .420 24 (Ref.) .001 8 (Ref.)
2 12 3 12.83 (2.46–66.92) 3 1.64 (0.49–5.49) 3 7.00 (1.77–27.64)

PSA indicates prostate-specific antigen; T, tumor size; N, nodal status; HR, hazard ratio; CI, confidence interval; Ref., reference. Significant P values are bolded.