Table 1.

Comparison of BEGIN^® Once Simple titration algorithms

Pre-breakfast SMBG		Dose adjustment IDeg Simplea	Dose adjustment IDeg Step-wiseb
mmol/L	mg/dL	U	U
<3.1	<56	−4	−4
3.1–3.9	56–70		−2
4.0–5.0	71–90	0	0
5.1–7.0	91–126	+4	+2
7.1–8.0	127–144		+4
8.1–9.0	145–162		+6
>9.0	>162		+8

IDeg insulin degludec, SMBG self-measured blood glucose

^aBased on a single measurement on the day of titration

^bBased on the lowest of 3 consecutive days’ measurements