Table 2.
Risk for bipolar disorder and schizophrenia in relatives to probands with ADHD and controls matched on birth year and gender.
| Bipolar disorder in relatives |
Schizophrenia in relatives |
|||||
|---|---|---|---|---|---|---|
| Probands N (%) |
Controls N (%) |
OR (95% CI) |
Probands N (%) |
Controls N (%) |
OR (95% CI) |
|
| First-degree relatives | ||||||
| Parents | 986 (0.95) | 4835 (0.51) | 1.84 (1.72–1.97) | 366 (0.35) | 1503 (0.16) | 2.22 (1.99–2.47) |
| Offspring | 52 (0.28) | 187 (0.12) | 2.54 (1.92–3.35) | 15 (0.08) | 75 (0.05) | 1.89 (1.13–3.15) |
| Full siblings | 319 (0.52) | 1212 (0.23) | 2.22 (1.98–2.50) | 142 (0.23) | 676 (0.13) | 1.71 (1.44–2.04) |
| Second-degree relatives | ||||||
| Maternal half-siblings | 88 (0.44) | 135 (0.32) | 1.26 (1.01–1.58) | 33 (0.17) | 54 (0.13) | 1.11 (0.78–1.58) |
| Paternal half-siblings | 84 (0.38) | 132 (0.29) | 1.34 (1.06–1.71) | 44 (0.20) | 73 (0.16) | 1.06 (0.79–1.43) |