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. 2013 Jul 17;2013:879512. doi: 10.1155/2013/879512

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Copyright © 2013 Wanshuai Li et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Xiao-Ai-Ping promotes the antigrowth and proapoptotic effects of cisplatin on LLC xenografts. PBS (Vehicle, n = 8), 1 mg/kg cisplatin (Cis, n = 8), 20 g crude/kg Xiao-Ai-Ping (Xiao, n = 8), and 1 mg/kg cisplatin plus 20 g crude/kg Xiao-Ai-Ping (Cis+Xiao, n = 8) were daily injected for 21 days, respectively. Tumor sections were infused in formaldehyde solution for immunohistochemistry. (a) Expression of PCNA (left panel) and average optical density of five samples (right panel). (b) Expression of phospho-Akt (left panel) and average optical density of five samples (right panel). (c) Expression of CHOP (left panel) and average optical density of five samples (right panel). (d) TUNEL staining of tumor sections (left panel) and average optical density of five samples (right panel). Images were representative of eight samples per group, and quantitation data were average of eight samples. Scale bars, 10 μm. *P < 0.05, **P < 0.01, ***P < 0.001.