Table 2. Correlation of clinicopathologic features and tumors response to H. pylori eradication therapy of gastric MALT lymphoma.
| Clinicopathologic characteristics | Tumors response to HPE | Pa | |
|---|---|---|---|
| |
HP-dependent (n=38) |
HP-independent (n=26) |
|
| Age (median, range, years) | 60 (30–86) | 58 (18–76) | 0.191b |
| Sex, male/female | 11/27 | 11/15 | 0.269c |
| Endoscopic features, n (%) | 0.036d | ||
| Gastritis-like or multiple erosion on infiltrative mucosa | 18 (47.4%) | 6 (23.1%) | |
| Ulceration or ulcerated mass | 16 (42.1%) | 13 (50.0%) | |
| Erosions on giant nodular folds | 3 (7.9%) | 6 (23.1%) | |
| Mixed | 1 (2.6%) | 1 (3.8%) | |
| Location of tumor (s), n (%) | 0.025c | ||
| Proximale or ⩾2 components | 10 (26.3%) | 14 (53.8%) | |
| Distalf | 28 (73.7%) | 12 (46.2%) | |
| Depth of gastric wall involvement, n (%)g | 0.034c | ||
| Submucosa or above | 28/35 (77.1%) | 13/24 (54.2%) | |
| Muscularis propria or beyond | 7/35 (22.9%) | 11/24 (45.8%) | |
Abbreviations: HP, H. pylori; HPE, H. pylori eradication therapy; MALT, mucosa-associated lymphoid tissue.
a
P: comparison of discrete variables between CagA expression-positive and CagA expression-negative.
b
P-values (two-sided) were calculated using the Student's t-test.
c
P-values (two sided) were calculated using χ2 test or Fisher's exact test.
d
P-values (two-sided) were calculated using one-way analysis of variance.
e
Proximal: Middle body, upper body, fundus or cardia.
f
Distal: Antrum, angle or lower body.
g
Gastric wall involvement was evaluated by endoscopic ultrasonography in 59 patients.