Table 2.
Microsatellite analyses in 105 pediatric high grade osteosarcomas (results expressed in patient numbers followed by the percentage, homozygous results are the non informative biopsies).
| Locus targets | Allelotyping Results | ||
|---|---|---|---|
| Normal | Allelic imbalance (AI) | Homozygous result | |
|
D20S107/D20S855 Combined results: 20q11 TOP1 locus 96 informative biopsies |
58 = 60.5% | 38 = 39.5% | 9 |
|
D17S800/D17S1818 Combined results: 17q21 TOP2A/ERBB2 amplicon 87 informative biopsies |
40 = 46% | 47 = 54% | 18 |
|
D3S700/D3S1283 |
26 = 33.5% | 52 = 66.5% | 27 |
| Combined results: 3p24 TOP2B locus 78 informative biopsies | |||