Table 2.
List of commonly used HDAC inhibitors.
| Chemical class | HDAC inhibitor | Reported targets |
|---|---|---|
| Benzamides | SNDX-275 (MS-275, Entinostat) | HDAC-1,-2,-3 |
| CI-994 (Tacedinaline) | HDAC-1, -2 | |
| MGCD-0103 | HDAC-1, -2, -3, 11 | |
| Short Chain Fatty Acids | Valproic acid (VPA) | Class I and IIa |
| Sodium butyrate | Class I and IIa, IV | |
| Phenyl butyrate (S-HDAC-42, AR-42) | Class I, II | |
| Cyclic Peptides | Depsipeptide (Romidepsin) | HDAC -1, -2 |
| Apicidin | Class I | |
| Hydroxamic Acids | JNJ-26481585 | Class I and II, IV |
| Suberoylanilide hydroxamic acid (SAHA; Vorinostat) | Class I and II, IV | |
| Trichostatin-A (TSA) | Class I and II, IV | |
| LBH589 (Panobinostat) | Class I and II, IV | |
| ITF2357 (Gavinostat) | Class I and II | |
| PXD101 (Belinostat) | Class I and II, IV | |
| NVP-LAQ824 (Dacinostat) | Class I | |
| Suberoylanilide bis-hydroxamic acid (SBHA) | HDAC-1, -3 | |
| RAS2410 (Resminostat) | HDAC-1, -3, -6 | |
| ACY-1215 (Rocilinostat) | HDAC-6 | |
| CR-2408 | Class I, II, IV | |
| Mercaptoketone | KD5170 | Class I and II |
| Others | Tubacin | HDAC-6 |